El padre de Annie, Charles, está visitando a la familia Camden, pero tiene una nueva novia, Ginger. Annie está realmente molesta porque su padre ya está viendo a alguien desde que su madre murió hace solo unos meses. Matt conoce a una chica en el aeropuerto, Heather. Más tarde, le pregunta una cita y se entera de que es sorda. Lucy sigue el consejo de Simon y se tiñe el pelo rubio. Mientras que en el parque, Mary se encuentra con un chico, Wilson y su hermano pequeño SUPERADO, Billy. Van a una cita más tarde esa noche. Al día siguiente en la iglesia, Annie sale corriendo. Mary decide seguir a su madre, pero es atropellada por un auto que corre a toda velocidad cuando la persigue al cruzar la calle.

En el final de la primera temporada, Eric y Annie esperan que Mary salga de la cirugía después de su accidente automovilístico. El culpable que llevó a Mary fue porque Michael Towner se enfurece y se pelea con él. Matt también intenta reparar su relación con Heather. Wilson pronto confiesa a Eric y Annie sobre su condición de padre adolescente de Billy y se sorprenden. Lucy y Jimmy se separan después de que Jimmy se da cuenta de que Lucy se ha teñido el pelo de rubio y se ha apagado. Mientras tanto, Annie arregla su relación con su padre y su nueva novia Ginger con consejos útiles de la Sra. Bink (estrella invitada Eileen Brennan). Por último, Eric y Annie reciben la noticia del cirujano de Mary de que podría ser una larga recuperación para ella, especialmente al jugar al básquetbol nuevamente.

En la apertura de la segunda temporada, Eric y Annie renuevan sus votos, se van a casar nuevamente. Los niños no están realmente entusiasmados con la boda, pero Ruthie quiere usar un esmoquin. Mary está cansada de caminar con muletas, pero teme que pueda caerse si no las usa. Lucy todavía está enojada porque Jimmy Moon está saliendo con Ashley ahora, pero los invita a la boda; más tarde, la ONU los invita. Matt y Heather pasan tiempo juntos antes de que ella se vaya a la escuela. Simon decide esperar antes de mudarse a su nueva habitación en el ático. Eric ayuda a una mujer, Nora, a hablar con el tipo que mató a su esposo hace unos años.

Mary intenta hacer que Wilson diga que él la "ama", pero Wilson cree que es un gran compromiso y que no se conocen desde hace mucho tiempo para decirse esas palabras. Mientras tanto, Simon y Ruthie leen las cartas de amor de Matt a Heather y las atrapan. Matt los engaña dirigiendo una de las cartas a la "Sra. Matt Camden". Por esto, Eric encuentra accidentalmente la carta que lleva a pensar que Matt y Heather se casaron durante el verano, lo que le preocupa a él, a la madre de Annie y Heather, la Sra. Cain. Por último, Eric ayuda a la amiga de Lucy, Laurie a acercarse más a su madre.

Eric acusa a Matt de consumir drogas después de encontrar marihuana en la casa y luego de que el amigo de Matt, Mitch, le pide que sostenga su marihuana. Mientras tanto, al mismo tiempo que Eric encuentra la marihuana en la casa, Annie lleva a una confesión sobre su experimentación. Además, Simon le enseña a Ruthie sobre el arte de lavar la ropa, aunque Ruthie es demasiado joven. Por último, Lucy presenta a su familia su nueva ropa de negro y su nuevo novio Rod.

Los niños de Camden aprenden una lección de amor cuando Mary decide renunciar a Wilson. Simon está obsesionado con tener a su primera novia, mientras que Ruthie aprende lo que hay que hacer y lo que no se puede hacer de besar en el patio de la escuela. Matt recibe noticias devastadoras de su novia Heather, que lo lleva en un largo viaje a Filadelfia. Mientras tanto, Lucy se lamenta de estar soltera hasta que accidentalmente se acerca al problema de la escuela.

Cuando Eric ayuda a su amigo el Reverendo Morgan Hamilton a encontrarse en secreto con el ex marido de su esposa Kevin, se sorprenden por el resultado de que está paralizado de cintura para abajo. Mientras cubría a la hija de Hamilton, Keesha, Lucy inesperadamente tiene una cita doble con ellos. Pronto, Annie y la Sra. Hamilton detienen a las chicas cuando llevan a Ruthie y Lynn al cine. De vuelta en la escuela, Mary sale clandestinamente con uno de los compañeros de clase de Lucy.

Lucy recibe una invitación para comer pizza con dos amigos rebeldes, y luego se culpa por el trágico accidente automovilístico que reclama la vida de su amiga y su hermana en el hospital. Después de que matan a la amiga de Lucy, la familia se reúne a su alrededor, notando su comportamiento inusualmente distante. Además, Mary le hace un favor a su ex novio Wilson y cuida a su hijo Billy para que pueda ir a su baile de graduación. Además, Simon consigue su propia habitación mientras Matt se muda al ático.

Cuando Mary y Wilson deciden volver a estar juntos, comienza a hacer que Annie se preocupe por su unión, ya que Wilson y su hijo Billy andan mucho más por la casa de Camden. Más tarde, Matt atrapa a Wilson y a Mary durmiendo juntos en su cama y les lanza un ataque. Mientras tanto, Lucy también está preocupada cuando sus ex novios, Jimmy Moon y Rod se unen para seguir a Eric por un proyecto de clase. Los dos muchachos incluso comienzan a llamarse a sí mismos "MIT's: Minister's In Training" de Eric. Además, Simon comienza a entrenar a Happy para un papel en un comercial de perros, mientras que Matt está buscando el momento adecuado para decirle a su familia que consiguió un trabajo en Washington DC durante el verano. Finalmente, después de que Happy gane el concierto comercial y se emita en la televisión, el propietario original de Happy y su hija ven a Happy en la televisión y la quieren de vuelta

En el final de la segunda temporada, Eric y Annie se sorprenden y entristecen de que Mary pueda estar embarazada después de hablar con su médico por teléfono. Mientras tanto, Matt hace un anuncio de que se va a casa antes de lo esperado para que pueda comenzar un programa de entrenamiento de verano en Washington DC. Sin embargo, Matt pronto se da cuenta de que "El Coronel" fue la verdadera razón de cómo ingresó al programa y debe decidir si Él debería tomarlo o no. Además, Simon y Ruthie están abatidos cuando el dueño original de Happy viene a reclamarla. Luego, la familia hace todo lo posible por recuperarla. Además, el padre de Annie, Charles y Ginger crean un compromiso falso para desalentar a Eric y Annie cuando intentan rescatar a Happy con el resto de la familia, pero más tarde hacen que el compromiso sea real. Por último, una gran sorpresa espera a Eric y Annie mientras descubren algo maravilloso.

The first weekend all seven siblings are home, Eric and Annie plan to extend their child-labor scheme to baby-sitting the noisy newborns. Matt starts his new job at the Dairy Shack, but can't stick it out with the owner's son as his hostile boss, but the evening holds one happy surprise for him. Mary slips away to meet Wilson and runs into Jordan, while Lucy does double chores. Happy is neglected and Ruthie feels neglected, and Eric ignores Simon's well-read parenting tips and steals his Dairy Shack order. Which family member restores heavenly peace to the household?

Eric threatens Robbie with eviction because he thinks he's keeping secrets about Mary. The house is abuzz with secrets and preparations for an elaborate surprise party for Eric's birthday. Johnny drops Mercy on the Camdens' doorstep after Frankie abandons them. Mike trusts Lucy enough to look after his mother for a day, during which the woman surprises her, both by speaking and by what she says.

Robbie is told last, despite Camden's advice for her to be open, that Mary has bumped into her ex Wilson, who does a course in Buffalo, and agreed to a dinner at his place. Robbie is doubly vexed as he immediately calls her after meeting a lookalike, Marie, also a basketball player, whom he asked over to get hold of her study notes. Matt meets and dates Cheryl before he realizes she's Robbie's ex. Mary also bumps into Lucy's Jeremy.

Robbie panics when Mary announces she's returning for the summer months, so he tells her to follow parental instructions not to date her all that time. Mike inspires Lucy how to stay with Jeremy now he's accepted to Juliard: marriage, so they get engaged. Matt is dumped by Cheryl for not telling the family about them, but that gives him the courage and more reward then he bargained for. Wilson was dumped but traveled all the way home, just when Mary's claim of sexual intimacy with Jeremy make Robbie deck Lucy's equally startled fiancé. Simon and Tim discover Deena dated each of them behind the other's back. Serena abuses her lonely birthday to make a move on therapist Eric, while hardware shopkeeper James Carver courts long-oblivious Annie.

Robbie gathers the courage to tell Mary openly, now her lies are exposed, their relationship is over, staying with the family his priority. Simon nurses his broken heart on account of Deenah, refusing to become 'just friends' again. Wilson bonds, while bunking, with Matt and Robby, and demands for Mary to return and go steady in New York, or break up completely. Jeremy forgives Lucy for doubting her fiancé's fidelity. Ultimately Eric helps her transfer to his New York alma mater, near Juliard. The Camden parents finally realize Serena and James are seducing them, ward off each suitor and match the lonely hearts.

Robbie remains inconsolable since Mary left with Wilson. The Colonel figures she won't go to college but marry and be a mother to Billy, so he insists on a job, preferably in public service, but he nor Wilson are pleased she opts for the police or fire department. Lucy refuses to explain why she left the New York seminary, apparently after a break-up with Jeremy, and Robbie is parentally dissuaded as consoling company. Annie works out her pre-menopause frustration on Eric, and he takes it out deviously on model student Simon for just a bit of attitude. Matt loses his hospital orderly job, but soon gets another: in a free clinic with mainly teenage and young-adult mothers-to-be.

Robbie amuses sneaky cookie-thief Ruthie by nicknaming her Snookie and sets straight Lucy's far less flattering interpretation. Wilson diplomatically handles Mary's absurd blaming him for her failed fire department application after she set fire to the colonel's curtains. Despite Eric's continuous meanness, Simon acts most responsibly when a kid only he, not even a teacher, defended against school bullies mentions planning to shoot them. Eric confronts the supervisor of a firm's staff where 'pranks' extend to stealing a prosthetic arm an counsels his ex Merle on forgiveness.

Robbie offers to pay $200 rent for the garage apartment if it ever gets finished. However, the siblings all want it, so Matt is promised a switch with his room and the others are jealous. Billy clearly pretends to be 'really' sick to make Mary stay with him and perhaps become his mama. Lucy promises handyman Ray Rickey work on the garage apartment, but the crook fakes a fall and has a leech-lawyer waiting.

Robbie introduces Lucy to his friend Hugh, feeling she should date again, but gets jealous enough to separate them with lies. Matt stands up against the free clinic's staff and gets Hank to overrule Dr. Kent's diagnose-and-operate routine. Feeling incompetent as a waiter at Pete's Simon resigns, but he gets promoted because of his business-planning skills. Cued by Billy via George, Wilson and Mary (who is failing in firefighter training) realize it's time to decide whether to commit to becoming a family.

Insecure Robbie hides his budding rebound-affair with Lucy. Wilson is deeply hurt when he finds fickle 'bride' Mary kissing fire-department coursemate Ben Kinkirk. Simon doesn't enjoy bully-mate Rick's girl abusing him as excuse to dump him. Annie's flippant advice nearly wrecks pupil Christy Parks' parents' marriage, yet she resists help even from Eric.

Robbie and Lucy gather the courage to tell everybody about their affair, only to find they all knew and don't really care. Without the thrill of sneaking, their first date fizzles. Ben Kinkirk and Mary both pass the firefighters course, but their meeting on whether to celebrate with classmates messes up Mary's reconciliation with fiancé Wilson., and Billy's questions make Wilson decide against her plan to elope. Matt discovers that Hank and Julie are planning a divorce, and Eric and Annie try to find out why and see if they can help fix it.

Wilson is amused that all the Camdens call him after Mary's sudden return home, but wants her to tell them what happened. Robbie makes clear he's no longer interested at all in her or Lucy, having found a potential bride. The siblings however are furious when their wayward sister gets the royal treatment from their mother, while their better behavior yielded nothing. It's the last straw when the garage apartment they all want is thrown in, so they squat. Annie declares a war of attrition on them. Eric cowardly keeps out and hopes his sermon on the prodigal son may smooth things, but everyone feels targeted.

The next Valentine's day, Robbie prepared a surprise for Joy. Mary meanly supposes the hotel she overheard him contacting by phone means another sex trap. Joy, who assumed the butler to be away like her father really is, isn't discouraged, but bitterly claims Robbie doesn't love her truly because he refuses to risk getting intimate. Matt contacts all his 'true lovers', wondering why he never stayed hooked up. Lucy again assumes Jeremy, who is back in town and double-dating with Mike, wants her back and pretends to have a date. Mary is shocked to see Wilson moved back and goes steady with her former school friend Corey Conway. Simon gets permission to let his hot senior date Maria 'help babysit' and gets her cute kid brother Jake to spare Ruthie dateless embarrassment.

Lucy and Kevin see a new doctor for their pregnancy and they have different opinions of her. Ruthie becomes interested in Martin's friend and starts wearing makeup and acting older. Charlie, the new father of Leanne's baby, is having a hard time and wants out of parenthood, so Eric enlists the help of an old, dear family friend.