Pregnant Karen Sawyers is murdered and her blood-stained husband Pete found wandering the streets but DI Naomi Silva turns her attention to Karen's lover, Adam Hayes, who was treating her at his clinic and had arranged for her to have a termination. Then Adam is also found dead. Clarissa finds evidence that Karen was being blackmailed with threats of Pete getting her medical records. This leads Naomi and Nikki to hospital head Simon Laing, who tells them a computer hacker calling himself Splinter stole patients' files though Simon kept it quiet for fear of tarnishing the hospital's reputation. Meanwhile barrister Jason Farrell is viciously attacked and left to die.

With Jason in a coma the police, given his hospital attendance, assume he was Splinter's latest victim though he was not robbed. A known hacker Gary Brockham is arrested and admits to selling hospital files on the dark web whilst Laing must admit his use of a questionable computer system company. He too is killed before a secret from the past resolves the case.

Sam Ryan recruits the Lyell team to investigate the assassination of the health secretary, but Nikki is unsure whether Sam knows more than she's letting on.