Cecilia breaks up with Martin because she wants to be with Simon. Matt continues to run into a former girlfriend and is concerned about his marriage falling apart. Ruthie's foreign exchange student visits and is now living with the Camdens.

Cecilia's dad George Smith tells Eric that he and his wife Gwen are looking for a foster-son, about 10 years old, to fill the now empty-feeling home, with the hope of adopting. The enthusiastic reverend immediately thinks of orphanage boy Danny Davies, who proves charming and eager. Danny expects to that his sisters will be adopted too. It's only fair that Eric helps put that straight, which proves even more complicated then it sounds. Carlos tells Matt he's leaving New York for his dad's firm in Puerto Rico because 'mother' Mary makes no marital effort at all, having cheerfully signed over custody of baby Charlie. The twins are sad that Martin, and in time all their siblings seem to leave, even Lucy now. Kevin presses her to finally choose a house, then concludes the mother is the one who pushes fledglings out of the nest. Simon's girlfriend Rose wants to dump him unless he gives a good reason why they still don't have sex. Vincent pushes Martin to help him break up with Ruthie, in case he meets a girl while on vacation with his grandparents on Hawaii.