Rudy takes Jess,Finn and Alex to a party held by his drug-loving friend Richard,where they discover they have the number of their sexual partners indelibly written on their foreheads. Richard is cowering in a cupboard,terrified of 'the White Rabbit',an apparent mutant. Bored with the party Finn and Rudy gate-crash a funeral where Rudy talks to the enigmatic Nadine,who rushes away mysteriously at midnight. Following her he is pursued by the giant white rabbit,which has just killed a girl but he escapes and gathers the boys together in time to rescue Jess from the rabbit,helped by a party-goer called Abbey. Next day Alex shows Jess why they cannot have sex. His penis was stolen by a transgender man.

Abbey sticks around at the Community Centre,claiming to be on community service when Greg questions her presence. She meets Tara from an ante-natal class who does not want her baby and transfers it to Abbey. However Abbey initially wants to keep the child,admitting that she lost her memory in the storm and wants something to make her feel she belongs. When Tara returns though Abbey feels sorry for her and reverses the process. Alex locates James, the transgender man who took his penis and tracks him down to a karaoke club, where the other misfits are amazed to see the threatening Greg sing a sensitive song. James gives Alex back what is his. Nadine turns up to see Rudy but rushes away again and when he follows her he discovers that she is a nun.

Rudy is perturbed that the nuns try to prevent him from seeing Nadine and,along with Abbey and Finn - who have just had sex - rescue her from the convent. However Alex's new-found masculinity has made him sexually selfish and Finn argues with him since he has cheated on Jess. Being confronted by anger which stresses her out unfortunately unleashes Nadine's special power - the ability to summon the Four Horsemen of the Apocalypse,which she does despite herself. The misfits are attacked by the horsemen and,although Finn uses his special power to save Abbey,Nadine sacrifices herself to make them disappear for good,leaving Rudy heart-broken. Alex is also stabbed and rushed to hospital.