Leo gives evidence at a custody hearing in the wake of a child's death,his opinion over-ruling that of Dr Helen Karamides,which annoys her former pupil Nikki,who sees Helen as the victim of the male establishment and cannot believe the accusation that Helen is retaining tissue samples from past cases. Nikki is also approached by Andy Farmer. His mother Annie was the appropriate adult at the interview with serial killer Arnold Mears,who now directs Annie to the sites of his victims' remains where she collects their bones. Andy wants Nikki to help identify them. Nikki also discovers that Helen had a professional involvement with Mears.

Leo feels guilty when Helen kills herself,leaving an explanation on Camcorder that she took the tissues to further scientific research. Aware that Mears killed more women than he was imprisoned for, Leo tells the police about the arrangement with Annie,scaring Andy, who believes that Mears will have his mother murdered for the breach of trust. It is also revealed that Annie believes her daughter was one of Mears' victims,hence her involvement with him. When Annie disappears Nikki visits Mears,who agrees to tell her about all his other victims. He appears to have won his mind game with her but his possessiveness over his copy of 'Paradise Lost' and Nikki's chance remark about an elderly lady she met who knew Mears yield results.