Después de los eventos de Over The Wild Green Yonder, Leela queda en coma irreversible. Fry debe encontrar una forma de lidiar con su pérdida, así que construye un Leela robótico.

Zapp and Leela are alone on an unknown planet after their mission to destroy a death star fails, while the rest of the gang tries to save Earth from being the star's next victim.

Fry y Bender compiten para ver quién puede conseguir más seguidores en su aplicación similar a Twitter en sus nuevos teléfonos oculares, sin saber que en realidad es parte de la malvada conspiración de Mamá para liberar un nuevo virus en los cerebros de las personas.

Amy gets together with Bender after Kif breaks up with her, which catches the ire of Dr. Farnsworth and others who oppose human-robot relationships.

Professor Farnsworth accidentally uncovers the blueprint for a mysterious Leonardo da Vinci invention, and he and his crew travel to Rome for answers.

Bender descubre que no tiene capacidades de respaldo, lo que significa que es mortal, y él y Hermes viajan a México para que pueda desahogar su frustración con su inspector.

Fry acepta viajar un minuto hacia el futuro en la nueva máquina del tiempo de Farnsworth justo antes de una gran cita con Leela, pero terminan yendo mucho más en el futuro sin forma de regresar en el tiempo.

A sinister cat uses Amy's failed dissertation to launch his plan to save his home planet by destroying Earth.

Después de una disputa con los creacionistas, Farnsworth huye con los demás a un planeta remoto e inhabitado. Al liberar microrobots en un estanque, comienza a evolucionar vida no orgánica en el planeta.

El experimento de intercambio de cuerpos del profesor produce un resultado que él no tenía en mente.

Lrrr is being pressured to conquer Earth.

Fry revela accidentalmente que Leela es una mutante, por lo que es desterrada a las alcantarillas donde deben vivir todos los mutantes. No dispuestos a aceptarlo, Leela y Fry organizan la revuelta de los mutantes contra esta segregación.

Three separate holiday stories: X-mas, Robanaca and Kwanzaa. 1. Once more Robot Santa comes to town. Besides the violence he spreads, this time he sings to the crew of the pine tree that are needed for a proper "X-mas". The only problem is that the pine trees have been extinct for over 800 years. However they manage to get some seeds, reforesting the earth. As the oxygen levels explode Bender causes the whole earth to catch fire. 2. Several weeks later, out of laziness Bender insists on celebrating the fake "Robanaca". For the traditional oil wrestling he needs petroleum oil but all petroleum resources are empty. The Professor tells him that a small quantity might be left, buried deep inside the earth and the quest begins. The ship crashes and 500 Million years later Bender alone returns to the surface bringing with him petroleum oil that originates from the remains of the others. 3. The unrelated conclusion: Everybody are celebrating "Kwanzaa" at Hermes' home. Kwanzaa-bot breaks through the wall and explains the tradition of Kwanzaa where beeswax plays is needed for the special Kwanzaa-candles. Of course they have run out of it, so they have to fly to the space bees hive to get some. When they arrive they find out the bees are infected and going crazy. Finally the spirit of Kwanzaa kills the parasites and the space bees unite to attack the crew.